A Sonochemically Activatable Pro-Molecular Glue for Spatiotemporally Controlled Targeted Protein Degradation
Angew. Chem. Int. Ed., e7024563 (2026)
Research outputs
Publications
Explore the work behind our research. Open a record for its abstract, citation, and available files.
Accepted conference papers
Accepted work awaiting proceedings publication. Available preprints are linked below.
- ACM MM 2026 · AcceptedAnyAvatar: High-Fidelity Gaussian Head Avatars under Uncalibrated Camera Settings
- PRCV 2026 · AcceptedLearning Whole Slide Image Representations from Few High-Resolution Patches via Cascaded Dual-Scale ReconstructionPreprint available; conference citation pending.
- PRCV 2026 · AcceptedMoGaFace: Momentum-Guided and Texture-Aware Gaussian Avatars for Consistent Facial GeometryPreprint available; conference citation pending.
- ACM MM 2026 · AcceptedMPFusion-MIL: Morphology-Guided Fusion with Precise Cross-Scale Interaction for Whole Slide Image Analysis
- ECCV 2026 · AcceptedPyraE2E: Enhancing End-to-End WSI Analysis via Cross-Scale Super-Resolution
Publication index
91 records · 2011–2026 · Newest first
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2026
An electron-density point-cloud framework for robust protein-ligand interaction prediction
Nat. Commun., 17(1), 7424 (2026)
PyraE2E: Enhancing End-to-End WSI Analysis via Cross-Scale Super-Resolution
ECCV, 2026 — Accepted
MPFusion-MIL: Morphology-Guided Fusion with Precise Cross-Scale Interaction for Whole Slide Image Analysis
ACM MM, 2026 — Accepted
AnyAvatar: High-Fidelity Gaussian Head Avatars under Uncalibrated Camera Settings
ACM MM, 2026 — Accepted
2025
Dynamic Reaction Path Descriptors: Integrating Mechanistic Insights for Enhanced AI-Driven Reaction Prediction
ChemRxiv, preprint (2025)
Anti-Triggering Receptor Expressed on Myeloid Cells 2-Conjugated Nanovesicles Loaded Vadimezan Reprogram Tumor-Associated Macrophages to Combat Recurrent Lung Cancer
ACS Nano, 19(36), 32674-32692 (2025)
Minimal High-Resolution Patches Are Sufficient for Whole Slide Image Representation via Cascaded Dual-Scale Reconstruction
Conference version accepted · PRCV 2026
arXiv, preprint, 2508.01641 (2025)
MoGaFace: Momentum-Guided and Texture-Aware Gaussian Avatars for Consistent Facial Geometry
Conference version accepted · PRCV 2026
arXiv, preprint, 2508.01218 (2025)
SyncAnimation: A Real-Time End-to-End Framework for Audio-Driven Human Pose and Talking Head Animation
IJCAI-25, 1657–1665 (2025)
Molecular tautomerism-induced formation of supramolecular hydrogel for mRNA enrichment and delivery
Cell Biomater., 1(8), 100124 (2025)
Machine Learning-Enhanced Nanoparticle Design for Precision Cancer Drug Delivery
Adv. Sci., 12(30), e03138 (2025)
Tuning Second Near-Infrared Fluorescence Activation by Regulating the Excited-State Charge Transfer Dynamics Change Ratio
J. Am. Chem. Soc., 147(20), 17330-17341 (2025)
2024
2023
A Bioactive Photosensitizer for Hypoxia-Tolerant Molecular Targeting-Photo-Immunotherapy of Malignant Tumor
In Adv. Funct. Mater.
Myeloperoxidase-Sensitive T1 and T2 Switchable MR Imaging for Diagnosis of Nonalcoholic Steatohepatitis
In ACS Nano
Anthracene-Bridged Photosensitizers for Effective and Safe Photodynamic Therapy
In Chem. Mater.
2022
Charge-Gradient-Induced Ferroelectricity with Robust Polarization Reversal
In Nano Lett.
High Exciton Utilization of 1D Molecular Column with High Packing Energy Formed by Folded π-Molecules
In J. Am. Chem. Soc.
From main-chain conjugated polymer photosensitizer to hyperbranched polymer photosensitizer: expansion of the polymerization-enhanced photosensitization effect for photodynamic therapy
In J. Mater. Chem. B
Cationization to boost both type I and type II ROS generation for photodynamic therapy
In Biomaterials
Enhanced Biological Imaging via Aggregation-Induced Emission Active Porous Organic Cages
In ACS Nano
2021
Self-Improving Photosensitizer Discovery System via Bayesian Search with First-Principle Simulations
In J. Am. Chem. Soc.
Photothermal-Activatable Liposome Carrying Tissue Plasminogen Activator for Photoacoustic Image-Guided Ischemic Stroke Treatment
In Small Struct.
Machine Learning-Assisted Robust Prediction of Molecular Optical Properties upon Aggregation
In Adv. Sci.
Accelerated Design of Near-Infrared-II Molecular Fluorophores via First-Principles Understanding and Machine Learning
In ChemRxiv
DNA oxidation mediated by [Ru(bpy)2tatp]2+ upon incorporation of [Co(phen)3]3+
In J. Electroanal. Chem.
An AIEgen as an Intrinsic Antibacterial Agent for Light-Up Detection and Inactivation of Intracellular Gram-Positive Bacteria
In Adv. Healthc. Mater.
Metabolizable Photosensitizer with Aggregation-Induced Emission for Photodynamic Therapy
In Chem. Mater.
A Polarity-Sensitive Ratiometric Fluorescence Probe for Monitoring Changes in Lipid Droplets and Nucleus during Ferroptosis
In Angew. Chem. Int. Ed. Engl.
Revisiting Carbazole: Origin, Impurity, and Properties
In ACS Materials Lett.
A Self-Improving Photosensitizer Discovery System via Bayesian Optimization and Quantum Chemical Calculation
In ChemRxiv
Stereoisomerization during Molecular Packing
In Adv Mater.
Nanobody modified high-performance AIE photosensitizer nanoparticles for precise photodynamic oral cancer therapy of patient-derived tumor xenograft
In Biomaterials
Cancer-Cell-Activated in situ Synthesis of Mitochondria-Targeting AIE Photosensitizer for Precise Photodynamic Therapy
In Angew Chem Int Ed Engl.
2020
Physically Informed Deep Learning for Accelerated Photosensitizer Discovery
In Virtual AIChE Meeting
Tumor-Activated and Metal-Organic Framework Assisted Self-Assembly of Organic Photosensitizers
In ACS Nano
AIEgen-coupled upconversion nanoparticles eradicate solid tumors through dual-mode ROS activation
In Sci. Adv.
All-in-One Molecular Aggregation-Induced Emission Theranostics: Fluorescence Image Guided and Mitochondria Targeted Chemo- and Photodynamic Cancer Cell Ablation
In Chem. Mater.
All-in-One Molecular Aggregation-Induced Emission Theranostics: Fluorescence Image Guided and Mitochondria Targeted Chemo- and Photodynamic Cancer Cell Ablation
In Chem. Mater.
Constructing Adaptive Photosensitizers via Supramolecular Modification Based on Pillararene Host-Guest Interactions
In Angew. Chem. Int. Ed. Engl.
Nanostructural Control Enables Optimized Photoacoustic–Fluorescence–Magnetic Resonance Multimodal Imaging and Photothermal Therapy of Brain Tumor
In Adv. Funct. Mater.
2019
Molecular Design for High-Performance Luminogens with Aggregation-Induced Emission
NUS
Organic Small Molecule Based Photothermal Agents with Molecular Rotors for Malignant Breast Cancer Therapy
In Adv. Fun. Mater.
Precise Molecular Design for High-Performance Luminogens with Aggregation-Induced Emission
In Adv Mater.
Precise Molecular Engineering of Photosensitizers with Aggregation-Induced Emission over 800 nm for Photodynamic Therapy
In Adv. Fun. Mater.
Precise Deciphering of Brain Vasculatures and Microscopic Tumors with Dual NIR-II Fluorescence and Photoacoustic Imaging
In Adv. Mater.
2018
High-Resolution 3D NIR-II Photoacoustic Imaging of Cerebral and Tumor Vasculatures Using Conjugated Polymer Nanoparticles as Contrast Agent
In Adv. Mater.
A Cross-linked Conjugated Polymer Photosensitizer Enables Efficient Sunlight-Induced Photooxidation
In Angew Chem Int Ed Engl.
Simultaneous Increase in Brightness and Singlet Oxygen Generation of an Organic Photosensitizer by Nanocrystallization
In Small
Theranostic Nanodots with Aggregation-Induced Emission Characteristic for Targeted and Image-Guided Photodynamic Therapy of Hepatocellular Carcinoma
In Theranostics
Polymerization-enhanced two-photon photosensitization for precise photodynamic therapy
In ACS Nano
Polymerization-enhanced photosensitization
In Chem.
Photosensitizers with Aggregation-Induced Emission: Materials and Biomedical Applications
In Adv Mater.
Dibenzothiophene-S,S-Dioxide-Based Conjugated Polymers: Highly Efficient Photocatalyts for Hydrogen Production from Water under Visible Light
In Small
Photoacoustic Imaging: Bright Aggregation-Induced-Emission Dots for Targeted Synergetic NIR-II Fluorescence and NIR-I Photoacoustic Imaging of Orthotopic Brain Tumors
In Adv. Mater.
Visualizing Photodynamic Therapy in Transgenic Zebrafish Using Organic Nanoparticles with Aggregation-Induced Emission
In Nanomicro Lett.
Bright Aggregation-Induced-Emission Dots for Targeted Synergetic NIR-II Fluorescence and NIR-I Photoacoustic Imaging of Orthotopic Brain Tumors
In Adv. Mater.
2017
Biocompatible conjugated polymer nanoparticles for highly efficient photoacoustic imaging of orthotopic brain tumors in the second near-infrared window
In Mater. Horiz.
A light-up endoplasmic reticulum probe based on a rational design of red-emissive fluorogens with aggregation-induced emission
In Chem. Commun.
Photophysics of an Asymmetric Donor–Acceptor–Donor′ TADF Molecule and Reinterpretation of Aggregation-Induced TADF Emission in These Materials
In J. Phys. Chem. C.
Highly efficient photosensitizers with aggregation-induced emission characteristics obtained through precise molecular design
In Chem Commun.
Molecular Engineering of Conjugated Polymers for Biocompatible Organic Nanoparticles with Highly Efficient Photoacoustic and Photothermal Performance in Cancer Theranostics
In ACS Nano
High performance photosensitizers withaggregation-induced emission for image-guidedphotodynamic anticancer therapy
In Mater. Horiz.
Organic Nanocrystals with Bright Red Persistent Room-Temperature Phosphorescence for Biological Applications
In Angew Chem Int Ed Engl
A biosensor based on self-clickable AIEgen: a signal amplification strategy for ultrasensitive immunoassays
In Chem. Commun.
Rational Design of a Red-Emissive Fluorophore with AIE and ESIPT Characteristics and Its Application in Light-Up Sensing of Esterase
In Anal. Chem.
A Highly Efficient and Photostable Photosensitizer with Near-Infrared Aggregation-Induced Emission for Image-Guided Photodynamic Anticancer Therapy
In Adv. Mater.
2016
Cell Tracking: Organic Nanoparticles with Aggregation-Induced Emission for Bone Marrow Stromal Cell Tracking in a Rat PTI Model
In Small
Calix[4]resorcinarene-based branched macromolecules for all-optical photorefractive applications
In J. Mater. Chem. C
Organic Nanoparticles with Aggregation-Induced Emission for Bone Marrow Stromal Cell Tracking in a Rat PTI Model
In Small
Far Red/Near-Infrared AIE Dots for Image-Guided Photodynamic Cancer Cell Ablation
In ACS Appl Mater Interfaces.
A Porphyrin-Based Conjugated Polymer for Highly Efficient In Vitro and In Vivo Photothermal Therapy
In Small
A Photostable Far-Red/Near-Infrared Conjugated Polymer Photosensitizer with Aggregation-Induced Emission for Image-Guided Cancer Cell Ablation
In Macromolecules
Decoration of porphyrin with tetraphenylethene: converting a fluorophore with aggregation-caused quenching to aggregation-induced emission enhancement
In J. Mater. Chem.
Light-responsive AIE nanoparticles with cytosolic drug release to overcome drug resistance in cancer cells
In Polym. Chem.
Bioorthogonal Turn-On Probe Based on Aggregation-Induced Emission Characteristics for Cancer Cell Imaging and Ablation
In Angew Chem Int Ed Engl.
Structure-Dependent cis/trans Isomerization of Tetraphenylethene Derivatives: Consequences for Aggregation-Induced Emission
In Angew. Chem. Int. Ed. Engl.
A FRET probe with AIEgen as the energy quencher: dual signal turn-on for self-validated caspase detection
In Chem. Sci.
2015
Silole-Based Red Fluorescent Organic Dots for Bright Two-Photon Fluorescence In vitro Cell and In vivo Blood Vessel Imaging
In Small
A self-reporting AIE probe with a built-in singlet oxygen sensor for targeted photodynamic ablation of cancer cells
In Chem. Sci.
Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation
In J. Mater. Chem. B.
Tuning the singlet-triplet energy gap: a unique approach to efficient photosensitizers with aggregation-induced emission (AIE) characteristics
In Chem Sci.
Light-Up Probe for Targeted and Activatable Photodynamic Therapy with Real-Time In Situ Reporting of Sensitizer Activation and Therapeutic Responses
In Adv.Fun.Mat.
White-light emission strategy of a single organic compound with aggregation-induced emission and delayed fluorescence properties
In Angew. Chem. Int. Ed. Engl.
2014
2013
Terminally activated delayed fluorescence material, a method of synthesizing the same and an OLED device using the same
US Patent Appl.
Piezochromic Aggregation-Induced Emission Materials
In Prog. Chem.
Preparation of biocompatible aggregation-induced emission homopolymeric nanoparticles for cell imaging
In Macromol. Biosci.